ChloroquineV1, Main, Exploration, bibRecord, 003955

Prevention of postoperative thrombosis by aspirin

Identifieur interne : 003955 ( Main/Exploration ); précédent : 003954; suivant : 003956

Prevention of postoperative thrombosis by aspirin

Auteurs : Michael Hume [États-Unis] ; Benjamin Bierbaum [États-Unis] ; T. Xavier Kuriakose [États-Unis] ; Jeanne Surprenant [États-Unis]

Source :

The American Journal of Surgery [ 0002-9610 ] ; 1977.

RBID : ISTEX:65513F96C99B9D0CF9BC79632A4E8AA3A5089FC4

English descriptors

Teeft :
- American journal, Aspirin, Blood levels, Contrast phlebograms, Doctor hume, Endpoint, Endpoint criteria, Extensive thrombosis, Hydroxychloroquine, Impedance, Impedance plethysmography, Joint reconstruction, Michael hume, Monitoring technics, Phlebogram, Placebo, Platelet, Platelet function, Plethysmography, Postoperative, Postoperative venous thrombosis, Second phase, Serious bleeds, Surg, Technics, Thromboembolism, Thrombosis, Venous, Venous thromboembolism, Venous thrombosis.

Abstract

Abstract: In a random double-blind trial monitored by 125I-fibrinogen leg scan, impedance plethysmography, and contrast phlebograms if impedance became abnormal, hydroxychloroquine was shown to be no more effective than placebo for prevention of venous thrombosis after total hip replacement. Subsequently, the combination of hydroxychloroquine with aspirin was shown to be not significantly better than aspirin alone. Although the two parts of the trial were performed in an identical manner, comparison of the two sequential parts of this investigation, which provided a significant trend favoring aspirin, must be interpreted with caution. Further study including concurrent controls is needed.

Url:

https://api.istex.fr/ark:/67375/6H6-VFJQ7QCH-M/fulltext.pdf

DOI: 10.1016/0002-9610(77)90125-8

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000321
to stream Istex, to step Curation: 000321
to stream Istex, to step Checkpoint: 002703
to stream Main, to step Merge: 003A34
to stream Main, to step Curation: 003955

Le document en format XML

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<term>Contrast phlebograms</term>
<term>Doctor hume</term>
<term>Endpoint</term>
<term>Endpoint criteria</term>
<term>Extensive thrombosis</term>
<term>Hydroxychloroquine</term>
<term>Impedance</term>
<term>Impedance plethysmography</term>
<term>Joint reconstruction</term>
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<front><div type="abstract" xml:lang="en">Abstract: In a random double-blind trial monitored by 125I-fibrinogen leg scan, impedance plethysmography, and contrast phlebograms if impedance became abnormal, hydroxychloroquine was shown to be no more effective than placebo for prevention of venous thrombosis after total hip replacement. Subsequently, the combination of hydroxychloroquine with aspirin was shown to be not significantly better than aspirin alone. Although the two parts of the trial were performed in an identical manner, comparison of the two sequential parts of this investigation, which provided a significant trend favoring aspirin, must be interpreted with caution. Further study including concurrent controls is needed.</div>
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Prevention of postoperative thrombosis by aspirin

Prevention of postoperative thrombosis by aspirin

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri